On April 7th 2005 the U.S. Food and Drug
Administration issued a request to Pfizer to withdraw
Bextra from the market. The FDA cited increased
risks to users of the drug of stroke, heart attack and
serious skin reactions that could result in death.
Other reported side effects included angina and
Stevens-Johnson syndrome.
Cardiovascular risks
associated with Bextra were first acknowledged by
Pfizer in October 2004. Shortly after a study
released by the American Heat Association reported
that patients recovering from cardiac surgery were 2
times more likely to suffer a heart attack or stroke
if they were taking Bextra.
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