When drugs that have been approved by the FDA are shown to cause unexpected and dangerous conditions in patients, they can be recalled and withdrawn from the market.  Usually the risks did not surface during the Phase III clinical trials and only became apparent from wide-use patient experience.

Drugs that are now listed as dangerous drugs include:

• alosetron (2000) - withdrawn due to risk of fatal complications of constipation; reintroduced 2002 on a restricted basis
• bextra (2005) - withdrawn due to risk of cardiovascular events
• cerivastatin (2001) - withdrawn due to risk of rhabdomyolysis
• cisapride (2000s) - withdrawn in many countries due to risk of cardiac arrhythmias
• diethylstilbestrol (1970s) - withdrawn due to risk of teratogenicity
• duract (1998) - withdrawn due to risk of hepatitis
• Fen-phen - popular combination of fenfluramine and phentermine; phentermine remains on the market, dexfenfluramine & fenfluramine (1997) later withdrawn
• lysergic acid diethylamide (LSD) (1950s-1960s), marketed as a psychiatric cure-all; withdrawn after it became widely used recreationally by hippies
• methaqualone (1984) - withdrawn due to risk of addiction and overdose.
• meridia (1998) - withdrawn do to link to 19 heart attack deaths
• mibefradil (1998) - withdrawn due to dangerous interactions with other drugs
• phenformin and buformin - withdrawn due to risk of lactic acidosis
• rapacuronium (2001) - withdrawn in many countries due to risk of fatal bronchospasm
• rofecoxib (Bextra) (2004) - withdrawn due to risk of myocardial infarction
• terfenadine (1998) - withdrawn due to risk of cardiac arrhythmias; superseded by fexofenadine
• thalidomide (1950s-1960s) - withdrawn due to risk of teratogenicity; returned to market as an anti-neoplastic drug under FDA orphan drug rules
• ticrynafen (1982) - withdrawn due to risk of hepatitis
• triazolam (1991) - withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions
• troglitazone (2000) - withdrawn due to risk of hepatotoxicity; superseded by pioglitazone and rosiglitazone
   

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Dangerous Drugs News
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WLTX.comBath salts: a dangerous drug on the riseIndiana StatesmanForget about taking the risk of tracking down a dealer to buy weed, meth, or a baggie of your favorite pharmaceutical drug. Why not go to your local mini mart and pick up some bath salts I mean, something legal that we can ingest for a high, Officials want dangerous fake drugs off store shelvesU T San DiegoWarning Issued To Businesses Selling Synthetic DrugsKGTV San DiegoREGION: Authorities warn businesses against selling synthetic drugsNorth County TimesPrescott Daily Courier Payson Roundupall 42 news articles raquo
• Butte Judge Faces 12 Felony Dangerous Drug Charges Involving Methadone The R...
Butte judge faces 12 felony dangerous drug charges involving methadoneThe RepublicA Butte justice of the peace who authorities say doctor shopped to get multiple prescriptions for the painkiller methadone has been charged with 12 felony counts of fraudulently obtaining dangerous drugs. Robert quotBobquot E. Lee was charged Friday in Affidavit details alleged 39doctor shopping39Helena Independent RecordButte JP faces 22 more felony drug chargesFoxReno.comButte judge accused of 39doctor shopping39 for methadone prescriptionsBillings GazetteKXLF Butte Newsall 33 news articles raquo
• Cops Urge Early Drug Education Calgary Sun
Cops urge early drug educationCalgary SunOften drugs were bought and sold in lunch hour exchanges between children and high school students and drop outs in parking lots. He said it was disappointing to see some parents play down the dangers posed by what kids believe to be soft dope, and more raquo
• Drugsapos Framework Reform Sorely Needed But Not To Be Seen Jose Herrera Ma...
Drugs39 Framework reform sorely needed but not to be seen Jose HerreraMalta Independent OnlineThe law is too draconian for people caught with drug possession and minimal trafficking when there needs to be more emphasis on rehabilitation. The law as it is now, is also at odds with the European Convention for Dangerous Drugs, and which Malta has Drugs court reform 39cosmetic39Times of Maltaall 5 news articles raquo