Dangerous Drugs

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List of Dangerous Drugs

Drugs that have been withdrawn
from the market due to patient risks

When drugs that have been approved by the FDA are shown to cause unexpected and dangerous conditions in patients, they can be recalled and withdrawn from the market.  Usually the risks did not surface during the Phase III clinical trials and only became apparent from wide-use patient experience.

Drugs that are now listed as dangerous drugs include:

  • alosetron (2000) - withdrawn due to risk of fatal complications of constipation; reintroduced 2002 on a restricted basis
  • bextra (2005) - withdrawn due to risk of cardiovascular events
  • cerivastatin (2001) - withdrawn due to risk of rhabdomyolysis
  • cisapride (2000s) - withdrawn in many countries due to risk of cardiac arrhythmias
  • diethylstilbestrol (1970s) - withdrawn due to risk of teratogenicity
  • duract (1998) - withdrawn due to risk of hepatitis
  • Fen-phen - popular combination of fenfluramine and phentermine; phentermine remains on the market, dexfenfluramine & fenfluramine (1997) later withdrawn
  • lysergic acid diethylamide (LSD) (1950s-1960s), marketed as a psychiatric cure-all; withdrawn after it became widely used recreationally by hippies
  • methaqualone (1984) - withdrawn due to risk of addiction and overdose.
  • meridia (1998) - withdrawn do to link to 19 heart attack deaths
  • mibefradil (1998) - withdrawn due to dangerous interactions with other drugs
  • phenformin and buformin - withdrawn due to risk of lactic acidosis
  • rapacuronium (2001) - withdrawn in many countries due to risk of fatal bronchospasm
  • rofecoxib (Bextra) (2004) - withdrawn due to risk of myocardial infarction
  • terfenadine (1998) - withdrawn due to risk of cardiac arrhythmias; superseded by fexofenadine
  • thalidomide (1950s-1960s) - withdrawn due to risk of teratogenicity; returned to market as an anti-neoplastic drug under FDA orphan drug rules
  • ticrynafen (1982) - withdrawn due to risk of hepatitis
  • triazolam (1991) - withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions
  • troglitazone (2000) - withdrawn due to risk of hepatotoxicity; superseded by pioglitazone and rosiglitazone
     

 

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Is The AposBreakthrough Therapyapos Process Putting Dangerous Drugs On Store ...
Healthline Is the 39Breakthrough Therapy39 Process Putting Dangerous Drugs on Store Shelves Healthline As hoped, these drugs reached the market faster. In a study published this month in the New England Journal of Medicine, Darrow and his colleagues found that breakthrough drugs are approved on average three years faster than drugs that follow the usual

GIsapos Drug Use In Vietnam SoaredWith Their Commandersapos Help History
History GIs39 Drug Use in Vietnam SoaredWith Their Commanders39 Help History Armed servicemen of the Vietnam War used drugs more heavily than any previous generation of enlisted U.S. troops. From heroin to amphetamines to marijuana, drugs were so commonplace among the troops that, in 1970, liaison to the Bureau of Narcotics and and more raquo

Police Blotter: Resisting Arrest, Dangerous Drugs, Firecracker At The Acoma ...
Montana Standard Police blotter: Resisting arrest, dangerous drugs, firecracker at the Acoma Montana Standard Dangerous drugs. At approximately 4:30 a.m. Friday morning, officers on routine patrol on Harrison Avenue began to follow a vehicle they assessed was being driven suspiciously. They followed the vehicle into the parking lot of the Hampton Inn. When

AposGolden Gooseapos Of Xanax Sentenced In Bozeman Idaho State Journal
39Golden goose39 of Xanax sentenced in Bozeman Idaho State Journal A former Montana State University student who referred to himself as the golden goose of selling Xanax in Bozeman got probation after pleading guilty to distributing the drug. On Tuesday, Christopher Flanagan, 21, received a three year deferred

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