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Facts - Books - News    U.S. Facts Of Law:

Vioxx, COX-2 Selective Inhibitor

Vioxx, also known as rofecoxib, is a prescription drug that acts on one form of the cyclooxygenase (COX) enyme.  It belongs to the group of drugs known a NSAID's or COX-1 and COX-2 inhibitors.  Vioxx is a COX-2 inhibitor and acts to reduce pain and inflammation. Non-selective NSAID's such as aspirin and ibuprofen often times can cause peptic ulcers.  Vioxx, by being selective COX-2 inhibitor minimizes the adverse gastrointestinal effects.

Vioxx was widely prescribed to relieve arthritis pain and inflammation from its introduction in 1999 until 2004.  The drug was voluntarily removed from the market by the manufacturer, Merck, in 2004 after it was suspected to possibly have contributed to tens of thousands of deaths due to cardiac failure.


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Startup Seeking To Resurrect Vioxx, Arthritis Drug Pulled From Market STAT
STAT Startup seeking to resurrect Vioxx, arthritis drug pulled from market STAT RENTON, N.J. Could there be a second life for the once popular arthritis pill Vioxx A startup pharmaceutical company hopes so. Merck amp Co. voluntarily pulled the blockbuster drug in 2004 amid evidence that it doubled the chances of having a heart and more raquo

Towns Sue Pharmaceutical Companies Over Opioid Abuse Milford Mirror
Towns sue pharmaceutical companies over opioid abuse Milford Mirror litigation include asbestos and mesothelioma, pharmaceutical, consumer protection, environmental, sexual abuse litigation and personal injury. The firm39s attorneys have been appointed to leadership in numerous national multidistrict litigations

Small Study Suggests Ibuprofen Alters Testosterone Metabolism Ars Technica
Fortune Small study suggests ibuprofen alters testosterone metabolism Ars Technica Still, the stomach issues were enough to induce pharmaceutical companies to design more specific NSAIDs like Vioxx and Celebrex. These ultimately revealed an underlying risk of heart complications that turned out to be common among NSAIDs, including Ibuprofen May Affect Men39s Sexual Health, Study FindsDaily Hornet Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadismProceedings of the National Academy of Sciences Ibuprofen may increase risk of fertility issues in men, study suggestsThe Guardian CNN Oxford Academic Oxford University Press Business Insider all 183 news articles raquo

Simmons Hanly Conroy Welcomes Retired Judge As Shareholder AdVantage News
Simmons Hanly Conroy welcomes retired judge as shareholder AdVantage News The firm39s attorneys have been appointed to leadership in numerous national multidistrict litigations, including prescription opioids, Toyota unintended acceleration, BP Deepwater Horizon Oil Spill, DePuy Pinnacle, the Volkswagen emission scandal and

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Facts of Law about the drug vioxx cox2

Facts of Law - Vioxx Cox2