Vioxx, also known as rofecoxib, is a prescription drug that acts on one form of the cyclooxygenase (COX) enyme.  It belongs to the group of drugs known a NSAID's or COX-1 and COX-2 inhibitors.  Vioxx is a COX-2 inhibitor and acts to reduce pain and inflammation. Non-selective NSAID's such as aspirin and ibuprofen often times can cause peptic ulcers.  Vioxx, by being selective COX-2 inhibitor minimizes the adverse gastrointestinal effects.

Vioxx was widely prescribed to relieve arthritis pain and inflammation from its introduction in 1999 until 2004.  The drug was voluntarily removed from the market by the manufacturer, Merck, in 2004 after it was suspected to possibly have contributed to tens of thousands of deaths due to cardiac failure.

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Vioxx COX-2 Selective Ihibitor News
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• Merck Makes Deal To Settle Canadian Vioxx Lawsuits For Up To C37 Million Wa...
Globe and MailMerck makes deal to settle Canadian Vioxx lawsuits for up to C37 million Washington PostTRENTON, NJ Drugmaker Merck amp Co. said Thursday that it has reached a deal to settle all lawsuits in Canada over its recalled painkiller Vioxx, for up to 36.9 million Canadian dollars 36.5 million. Merck and attorneys representing hundreds of Merck to pay at least 21.8 million to settle Vioxx lawsuits in CanadaToronto StarMerck To Resolve Vioxx Litigation In Canada Quick FactsNASDAQall 229 news articles raquo
• Merck Frosst Loses Informationprotection Appeal Vancouver Sun
Merck Frosst loses information protection appealVancouver SunThe company has been in the public eye before, most recently due to the controversy over its heart drug Vioxx, the long term use of which has been linked to an increased risk of heart attacks and strokes. Last month, it settled a class action lawsuit and more raquo
• Merck: Making Money The Hard Way IRA
Merck: Making Money The Hard WayIRAMerck knows this experience all too well as a result of the voluntary withdrawal of its anti inflammatory drug Vioxx in 2004. Vioxx was introduced in 1999 and performed well for 80 million pain suffers until Vioxx was linked to increased risk of stroke and more raquo
• JampJ, Merck Amp Co Settle Risperdal, Vioxx Cases Pharma Times
JampJ, Merck amp Co settle Risperdal, Vioxx casesPharma TimesMeantime, Merck amp Co has entered into an agreement to resolve all claims related to its now withdrawn painkiller Vioxx rofecoxib in Canada. The US drugs major will pay at least C21.8 million about 21.5 million but not more than C36.9 million.and more raquo
• Pharmaceutical Giant To Settle Canadian Class Action Suit On Vioxx TheTyee.c...
InPharmPharmaceutical giant to settle Canadian class action suit on VioxxTheTyee.ca blogBy Tom Sandborn January 23, 2012 02:56 pm Merck, the American based pharmaceutical giant, announced on January 19 it will settle class action suits in Canada connected to its controversial pain medication Vioxx. The company39s announcement, which comes Merck pays 37m to settle Canadian Vioxx claimsInPharmall 2 news articles raquo