A Free Service Provided By



Legal Topics

Arbitration and Mediation
Car Accidents
Child Support
Child Custody & Visitation

Copyright Law
Criminal Law
Dangerous Drugs
DUI Drunk Driving

Elderly Laws
Employees' Rights
Estate Planning
Family Law
Immigration Law

Lemon Law
Medical Malpractice
Megan's Law
Mesothelioma & Asbestos

Probate & Estates
Product Recalls
Real Estate

Statute of Limitations

Taxes & the IRS
Traffic Violations
Workers' Compensation
Work Related Injury

Privacy Policy

Contact Us

About Us

Facts - Books - News    U.S. Facts Of Law:

Vioxx, Market Withdrawal

Vioxx was voluntarily withdrawn from the U.S. market on September 30, 2004 by manufacturer Merck.  The Vioxx market withdrawal was in answer to studies indicating a higher risk of cardiovascular event in regular users of Vioxx.

A study on Vioxx (VIGOR study) was published in 2000.  It indicated a 4 times increase of risk of heart attack or stroke in Vioxx (rofecoxib) patients compared to patients taking naproxen over a 1 year period.  Merck's researchers concluded the findings of the study showed a protective effect of naproxen in reducing heart attacks in high cardiovascular risk patients.

Merck commenced a study (APPROVe study) in 2001 to evaluate the effects of Vioxx on colorectal polyps.  The study also intended to further evaluate the cardiovascular risk of Vioxx.  The study was ended early when results showed patients taking Vioxx were at increased risk of cardiovascular risk compared to patients taking a placebo after 18 months on the therapy.

Merck voluntarily withdrew Vioxx from the market on September 30, 2004 after the APPROVe study was ended early.  In the same month, the FDA also provided Merck with new research that further supported increased risk of heart attack among Vioxx users.


Vioxx Market Withdrawal Best Sellers from

(no title)


Newsfeed display by CaRP

Vioxx Market Withdrawal News
GN News

This RSS Feed URL Is Deprecated
This RSS feed URL is deprecated, please update. New URLs can be found in the footers at

Still Feeling The Vioxx Pain The Pharmaceutical Journal
The Pharmaceutical Journal Still feeling the Vioxx pain The Pharmaceutical Journal At the height of its eminence in 2003, Vioxx represented 10.3 of all NSAID prescriptions in England, with more than 2.1 million prescriptions dispensed. More than 2.5 million prescription items of a competing COX 2 product, Celebrex celecoxib, which

Vioxx Pulled From Global Market Medscape
Vioxx Pulled From Global Market Medscape Sept. 30, 2004 Merck amp Co., Inc., announced today a voluntary withdrawal of rofecoxib Vioxx from the U.S. and worldwide market due to safety concerns of an increased risk of cardiovascular events, according to an alert from MedWatch, the U.S. Food

Timeline: The Rise And Fall Of Vioxx NPR
NPR Timeline: The Rise and Fall of Vioxx NPR September 2004: Merck withdraws Vioxx after a colon polyp prevention study, called APPROVe, shows that the drug raises the risk of heart attacks after 18 months. By the time Vioxx is withdrawn from market, an estimated 20 million Americans have taken

Merck To Pay 830 Million To Settle Vioxx Shareholder Suit Wall Street Journal
Wall Street Journal Merck to Pay 830 Million to Settle Vioxx Shareholder Suit Wall Street Journal The painkiller Vioxx continues to cost Merck amp Co., more than 11 years after the company yanked the drug from the market because it increased users39 risk of heart attacks and strokes. Merck said Friday it agreed to pay 830 million to resolve a class and more raquo

IMPORTANT NOTICE: This webpage is Copyrighted content.  No portion of this page may be copied to any other webpage, forum, blog or other domain page or offline publication without written permission from Violators will be prosecuted to the fullest extent of the law.

The information provided by does not constitute legal advice or any other type of advice and is provided for educational purposes only without warranty of any kind. has not reviewed the information on this page for accuracy and is not responsible for any errors, omissions or inaccuracies.  For legal advice you should consult a licensed attorney.


Copyright All Rights Reserved -
No Portion of This Page May Be Copied Without Written Permission

Facts of Law on the vioxx market withdrawal

Facts of Law - Vioxx Market Withdrawal