Vioxx (rofecoxib) is a non-steroidal
anti-inflammatory drug (NSAID) that was widely
prescribed for acute pain and inflammation including
symptoms from arthritis. The manufacturer,
Merck, withdrew the drug from the market in
September, 2004 after it was linked to an increased
risk of heart attack and stroke.
Over two million people world-wide had been
prescribed Vioxx since its approval in 1999.
Annual sales were at $2.5 billion.
Other NSAID's include aspirin and ibuprofen.
Those do not share the cardiovascular risks of Vioxx.
Unlike aspirin and ibuprofen, Vioxx is a selective
NSAID inhibiting only the COX-2 enzyme.
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